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GPL-TOX

GPL-TOX

Advantages of the GPL-TOX Profile

  • GPL-TOX directly tests for 11 unique compounds. Indirect screening provides an evaluation of 165 different toxic chemicals by testing specific metabolites. All of the information is assessed from a single urine sample.
  • GPL-TOX revolutionizes the development of testing by expanding the scope to include both the environmental pollutants and mitochondrial function metabolites. The Great Plains Laboratory, Inc. suggests that the comprehensive GPL-TOX profile be used as the initial screening test for patients with severe or chronic illnesses.
  • GPL-TOX uses the power of advanced mass spectrometry (MS/MS) and the specificity of multiple reaction ion monitoring. Conventional mass spectrometry is adequate for substances present in urine at high concentrations, but is inadequate for testing substances such as certain genetic, mitochondrial, and toxic chemical markers. These markers found at very low concentrations in urine disappear in baseline noise with conventional mass spectrometry. Typically, many different individual tests are necessary to determine the levels of each pollutant, but the new GPL-TOX technology makes it possible in one single test by measuring urinary metabolites.

View Sample Report

Environmental Pollutants Tested by GPL-TOX

  • Phthalates
  • Vinyl Chloride
  • Benzene
  • Pyrethrins
  • Xylenes
  • Styrene
  • Organophosphates
  • MTBE and ETBE
  • 2,4-Dichlorophenoxyacetic Acid (2,4-D)
 

Metabolites of Pollutants Tested by GPL-TOX

  • 2-Methylhippuric Acid (2MHA)
  • 3-Methylhippuric Acid (3MHA)
  • 4-Methylhippuric Acid (4MHA)
  • N-acetyl phenyl cysteine (NAP)
  • Phenylglyoxylic Acid (PGO)
  • 2-Hydroxyisobutyric Acid (2HIB)
  • Monoethyl Phthalate (MEP)
  • Dimethylphosphate (DMP) and Diethylphosphate (DEP)
  • 3-Phenoxybenzoic Acid (3PBA)
  • Thiodiglycolic Acid (TDG)
  • 2,4-Dichlorophenoxyacetic Acid (2,4-D)
  • Tiglylglycine (TG)
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